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产前治疗的生物工程策略

Bioengineering strategies for prenatal therapy

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Nature Biotechnology 刊文综述产前治疗的生物工程策略，梳理从胎儿外科手术到宫内酶替代治疗的发展脉络。文章引用脊髓脊膜膨出宫内修复随机试验、婴儿型 Pompe 病宫内酶替代治疗等临床证据，并讨论先天性膈疝气管封堵、下尿路梗阻分流等胎儿干预手段的疗效与器械问题。

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来源：Nature Biotechnology · nature.com

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